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Fig. 2 | Genome Biology

Fig. 2

From: Small RNAs mediate transgenerational inheritance of genome-wide trans-acting epialleles in maize

Fig. 2

Transgenerational DNA methylation changes resembled the nonrecurrent parent. a, b Inheritance of 19 hyper allelic tgDMRs (a) and 60 hypo allelic tgDMRs (b) in the MB6S3 line (upper panels). Genomic regions in corresponding DMRs were converted to the recurrent parent B73 (lower panels). The percentage was estimated by the average B73/Mo17 allelic ratio in each DMR using SNPs of all loci. c, d Examples of Chr8: 105,835,001–105,835,200 (c) and Chr1: 161,850,201–161,850,400 (d) displaying high (c) and low (d) methylation and siRNA levels in both MB6S3 and donor parent Mo17. Scales are 0–1 or 0.5 and 0–400 or 100 for normalized methylation and siRNA levels, respectively, in each DMR. Numbers represent average levels of DMR methylation and siRNA expression (RPTM). Double asterisks indicate a significant change between MB6S3 and the recurrent parent B73 (P < 0.05, one-way ANOVA test for methylation and two-tailed Student’s t-test for siRNA expression)

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