Placental methylome reveals a 22q13.33 brain regulatory gene locus associated with autism

Table 1 Functional categories of genes showing adjusted NHIP-associated expression in human cortex, differential expression in NHIP overexpressing cells, and known ASD risk (from Fig. 4d overlap)

	GO Terms
Genes	Chromatin organization	Regulation of transcription by RNA polymerase II	Histone modification	Rhythmic process	Dendritic spine	Regulation of biosynthetic process	Count
ARID1B	X	X				X	3
ASH1L	X	X	X			X	4
BRD4	X	X	X			X	4
CREBBP	X	X	X	X		X	5
EP300	X	X	X	X		X	5
HNRNPU	X	X		X		X	4
HUWE1	X		X	X			3
JMJD1C	X		X			X	3
KMT2A	X	X	X	X		X	5
PRKCA	X		X				2
RERE	X	X				X	3
SETD5	X		X				2
SMARCA2	X	X				X	3
ADNP		X		X		X	3
CUX1		X				X	2
FOXG1		X				X	2
GRIN1		X			X	X	3
NR1D1		X		X	X	X	4
NR2F1		X				X	2
POGZ		X				X	2
ZNF292		X				X	2
ARHGAP32					X		1
CPEB4					X	X	2
LRRC4					X		1
TNRC6B						X	1

ISSN: 1474-760X