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Fig. 4 | Genome Biology

Fig. 4

From: Polygenic transcriptome risk scores (PTRS) can improve portability of polygenic risk scores across ancestries

Fig. 4

Portability of PTRS for 17 quantitative phenotypes in UK Biobank. The portability of PTRS trained and calculated using GTEx EUR whole blood samples are shown in yellow with the PRS shown in gray. “EUR ref.” set is used as the reference population in the calculation of portability (see details in the “Methods” section) so that the portability is always 1. Recall that the absolute performance of PTRS is, on average, lower than PRS as shown in Fig. 3a and Additional file 1: Figure S3

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Genome Biology

ISSN: 1474-760X

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