Fig. 6

Colocalization and interactions between 4acC and histone modification marks. a Heatmap of 4acC and seven histone modification marks in genes with 1 kb upstream and downstream flanking regions. b Ratios (expressed as percentages) of peaks with histone modification marks for genes containing 4acC peaks. The peak number of each group is shown. Significant differences between the observed ratio and the expected ratio due to chance were analyzed by Fisher’s exact test, and the p values are shown. c, d Box plot of expression levels for genes marked or not marked by H3K27me3 (c) or H3K4me2 (d) in combination with 4acC or a lack of 4acC in gene body regions. The p values were calculated for significant differences between two groups by the Mann–Whitney U test