Fig. 3

Performance improvement with additional time points. The shaded area shows the 95% confidence interval for the (7 choose n) possible permutations of n measured time points that can be supplied to an algorithm. “Average” results are the performance achieved by taking a subset of the seven individual runs with a single late time point with a given algorithm and taking the median of their gene fitness effects. Joint results are obtained by running Chronos with a subset of multiple late time points simultaneously