Fig. 3

Cell-type enrichment of unannotated exon-exon junctions. Heatmap showing the cell-type enrichment results for novel exon-exon junctions similar to the one performed in the ASCOT study [24]. The X-axis shows the bins of the -10 log p-values for cell type specificity using a Mann-Whitney U test comparing coverage within a cell type to coverage in all cell types. Each of the cell types evaluated are shown on the Y-axis with the percent of exon-exon junctions annotated denoted by a color gradient from dark blue (0%) to light yellow (50%) to dark red (100%). The row and column means are shown with the same color scale. The column mean, Col.Mean, shows that the average percent of annotated exon-exon junctions decreases as the cell type specificity increases on the X-axis