Fig. 3
From: PUMAS: fine-tuning polygenic risk scores with GWAS summary statistics
![Fig. 3](http://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs13059-021-02479-9/MediaObjects/13059_2021_2479_Fig3_HTML.png)
Model-tuning performance on real GWAS data. A PUMAS performance on the EA training set. B Prediction performance on two validation sets for EA. C PUMAS performance on the AD training set. D Prediction performance on two validation sets for AD. The X-axis shows the log-transformed p-value cutoffs in PRS which is the tuning parameter of interest. The Y-axis indicates predictive R2. EA educational attainment, AD Alzheimer’s disease