Table 1 The definition of functional nucleosome states
Functional nucleosome states (HMM states) | Histone marks | Ave. no. of nucleosomes | Genomic location | Ave. spacing | Positioning score | Phasing score |
|---|---|---|---|---|---|---|
Elongation accelerator NucS1 (S1) | K79me2 | 3.99 | 5′-gene body | 185.00 | 7.97 | 5.84 |
Compacting organizer NucS2 (S2) | K9me3 | 8.49 | Distal | 195.00 | 8.48 | 10.82 |
Elongation stabilizer NucS3 (S3) | K36me3 | 5.82 | 3′-gene body | 192.50 | 8.06 | 2.93 |
Accessible booster NucS4 (S4) | K4me1 | 4.13 | Distal | 181.75 | 8.47 | 10.96 |
Primed intermediator NucS5 (S5) | K4me1/K27me3 | 4.56 | Distal/promoter | 183.25 | 8.75 | 11.58 |
Elongation terminator NucS6 (S6) | K4me1/K36me3 | 3.74 | 3′-gene body | 180.00 | 8.61 | 1.46 |
Elongation processor NucS7 (S7) | K4me1/K36me3/K79me2/K9me3/K27me3 | 5.32 | Gene body | 183.25 | 8.90 | 2.04 |
Transcriptional stimulator NucS8 (S9) | K4me3/K4me1/K27ac | 2.09 | Promoter | 175.00 | 6.07 | 21 |
Crowding controller NucS9 (S10) | K27me3 | 7.37 | Distal | 196.75 | 8.82 | 16.4 |
Elongation speeder NucS10 (S11) | K36me3/K79me2 | 4.55 | Gene body | 185.00 | 8.72 | 1 |
Elongation initiator NucS11 (S13) | K4me3/K4me1/K27ac/K79me2 | 4.67 | Promoter/5′-gene body | 183.25 | 7.81 | 7.39 |