Table 2 Genes assigned to FLS based on posterior probability of SNPs in enhancers

3

chr1

2

FLS

rs28411352, rs28489009, rs2306627

POU3F1; MANEAL

RSPO1; RHBDL2

INPP5B; YRDC; C1orf122; MTF1; SF3A3; FHL3

MTF1; GNL2; RRAGC; MYCBP; YRDC; C1orf122; SF3A3

YRDC; C1orf122; MTF1; SF3A3

MTF1; CDCA8; RRAGC; MYCBP; YRDC; C1orf122

4

chr1

1

FLS

rs4839319, rs4839318, rs77227025

PTPN22

RLIMP2; SYT6; BCL2L15

MAGI3; RSBN1; AP4B1; PHTF1 AP4B1-AS1; HIPK1; OLFML3

HIPK1; AP4B1- AS1; OLFML3

MAGI3; AP4B1- AS1; HIPK1; OLFML3

HIPK1; AP4B1- AS1; OLFML3

10

chr2

1

ALL

rs10175798, rs10173253, rs906868, rs7579944, rs1355208

LBH

LCLAT1

LBH

LCLAT1

11

chr2

2

ALL

rs34695944, rs56095903

REL

REL

REL; PUS10

12

chr2

3

FLS

rs1858037, rs1858036, rs11673987, rs11126035, rs906577

SPRED2

ACTR2; SPRED2

SPRED2

ACTR2; SPRED2; AFTPH; PPP3R1

20

chr3

1

ALL

rs73081554, rs185407974,

rs180977001, rs35677470, rs114584537

DNASE1L3; HTD2

ALCOX2

FLNB; FLNB-AS1;

ABHD6; RPP14; PXK

PXK; SLMAP; FLNB; FLNB-AS1; PDHB

FLNB; FLNB-AS1; PXK

PXK; FLNB; FLNB-AS1; PDHB; SLMAP

23

chr4

3

FLS

rs34046593, rs36020664,

rs11933540, rs6448434, rs6448432

SMIM20;

TBC1D19; STIM2

RBPJ

RBPJ

25

chr5

3

FLS

rs2561477

PDZPHIP

C5orf30

27

chr6

3

FLS

rs2234067, rs1885205, rs916287, rs4713969, rs879036

STK38; SRSF3

STK38; SRSF3; MAPK14

28

chr6

3

ALL

TCTE1

SPATS1; VEGFA

AARS2; NFKBIE

HSP90AB1; SLC35B2

NFKBIE

HSP90AB1; SLC35B2; NFKBIE

33

chr7

2

ALL

rs186735625, rs57585717, rs2158624

HOXA11; HOTAIRM1

JAZF1

JAZF1; HOXA10; HOXA11-AS;

CREB5

JAZF1

JAZF1; HOXA11- AS; CREB5

34

chr7

3

FLS, B CELL

rs4272, rs8179, rs42034

SAND9; HEPACAM2; VPS50

CDK6

CDK6; SAMD9; SAMD9L

CDK6

CDK6; SAMD9; SAMD9L

36

chr8

2

FLS, B CELL

rs2736337

BLK

TDH; GATA4; DEFB

38

chr8

2

FLS

rs678347, rs507201, rs657425

GRHL2

RRM2B

41

chr9

3

ALL

rs10985070

C5; PHF19; TRAF1

PHF19; MEGF9; CNTRL; FBXW2; PSMD5; GSN; GSN-AS1

PHF19; TRAF1

PHF19; TRAF1; CNTRL; FBXW2; GSN; GSN-AS1; PSMD5; STOM

46

chr10

1

ALL

rs12764378, rs71508903

RTKN2

ARID5B

ARID5B

ARID5B

ARID5B

48

chr11

3

ALL

rs968567, rs7943728, rs61896141, rs61897793, rs61897795

CD5

PTGDR2

FADS2; SLC15A3; TKFC; INCENP; CCDC86; PRPF19; TMEM109; TMEM132A; VPS37C; DDB1; CYB561A3; TMEM138; CPSF7; MYRF; FEN1; FADS1; FADS3; BEST1; FTH1

FADS2; FADS1; MYRF; FEN1; INCENP; FADS3; BEST1; FTH1; RAB3IL1; CCDC86; PRPF19; TMEM109

FADS2; SLC15A3; TKFC; INCENP; CCDC86; PRPF19; TMEM109; TMEM132A; VPS37C; DDB1; CYB561A3; TMEM138; CPSF7; MYRF; FEN1; FADS1; FADS3; BEST1; FTH1

FADS2; FADS1; MYRF; FEN1; VPS37C; INCENP; FADS3; BEST1; FTH1; CCDC86; PRPF19; TMEM109; TMEM132A; SLC15A3

56

chr14

2

ALL

rs1950897, rs911263, rs1885013, rs2104047, rs3784099

RAD51B

ZFP36L1

ZFP36L1

57

chr14

2

ALL

rs7146217, rs36045050, rs11158764

RAD51B;ZFYVE26

; ZFP36L1

ZFP36L1

ZFYVE26; ZFP36L1

ZFP36L1

67

chr20

2

ALL

rs4239702, rs4810485, rs1883832

CD40

SLC35C2; ELMO2

ELMO2; SLC35C2; NCOA5

68

chr21

3

ALL

rs73194058, rs11702844, rs11700997

SON; IFNGR2; ITSN1; TMEM50B; GART; DONSON; CRYZL1

IFNGR2; GART; SON; ITSN1; IFNAR1; PAXBP1- AS1; IL10RB-DT; DONSON; NDUFV3; ATP5PO

SON; IFNGR2; ITSN1; GART; DONSON

IFNGR2; GART; SON; ITSN1; IFNAR2; IFNAR1; PAXBP1; IL10RB- DT; IL10RB; DONSON; PTER

69

chr21

3

FLS

rs7278771, rs7283600, rs147868091

RCAN1

RCAN1

RCAN1

RCAN1

70

chr21

1

FLS

rs8133843, rs8129030, rs9979383

SET4; PPP1R2P2

RUNX1

RUNX1; CLIC6