Fig. 6

Predicted functional networks of genes that were associated with SNPs active in FLS. a A protein-protein interaction network was established using STRING with default settings (medium confidence). The obtained network had more interactions than expected by chance with a protein-protein-interaction enrichment p value of 1.28e−08. The thickness of the lines indicates the strength of data support. Colors, distances, and location on the map were assigned randomly. b Functional enrichment of genes interacting with SNPs active in FLS was detected using ToppFun in default settings. Significant terms for GO molecular function are shown. FDR = false discovery rate; B&H = Benjamini-Hochberg ; B&Y = Benjamini-Yekutieli