Fig. 4
From: Functional genomics atlas of synovial fibroblasts defining rheumatoid arthritis heritability
Heritability and causal SNPs in FLS. a Partitioned heritability (h2) of RA attributed to active regions in each sample of FLS (n = 7) and 111 available Roadmap cell types/tissues (Epigenomics Mapping Roadmap Consortium [11]). b The sum of posterior probability overlapping active DNA regulatory elements across blood and T cell samples (Epigenomics Mapping Roadmap Consortium; green bar), FLS samples (red bar), human stem cells (HCS), and B cells (Epigenomics Mapping Roadmap Consortium; blue bar) at each of the 73 sites. Active DNA regulatory elements were defined as the union of H3K4me3, H3K4me1, and H3K27ac marks