Fig. 1

Sfaira is a data and model zoo that automates common steps in exploratory single-cell RNA-seq analysis. a Overview workflow of sfaira data and model API. Data set files are currently stored in cloud databases that can be interfaced with the sfaira data API to give streamlined AnnData objects that can be used for analysis or model fitting. The sfaira model API can consume these data sets to produce automatised analyses by querying parameter estimates from pre-trained models stored on cloud servers via the sfaira parameter API. Example analysis steps that are automated are embedding computation and cell type annotation. b Summary of the current state of sfaira data zoo for mouse and human single-cell RNA-seq samples, representing 220 data sets and 8.0 million cells in two organisms