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Fig. 4 | Genome Biology

Fig. 4

From: INFIMA leverages multi-omics model organism data to identify effector genes of human GWAS variants

Fig. 4

Variable transcriptome across islets of founder DO strains. a Two-dimensional projection of the 91 founder RNA-seq samples with tSNE. Samples from wild-derived strains are boxed in with the red rectangle. b UpSet plot [50] for the frequencies of genotypes of local-ATAC-MVs associated with founder islet gene expression. Each gene with at least one significant association contributed its most significant local-ATAC-MV. Genotypes with frequencies less than 50 are not displayed

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