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Fig. 1 | Genome Biology

Fig. 1

From: Genomic diversity and ecology of human-associated Akkermansia species in the gut microbiome revealed by extensive metagenomic assembly

Fig. 1

The Akkermansia genus comprises four additional candidate species phylogenetically rooted between the already characterized A. glycaniphila and A. muciniphila. A Whole-genome phylogeny of the 2420 metagenome-assembled genomes (MAGs) reconstructed here and the genomes from isolate sequencing available in NCBI taxonomically annotated as A. muciniphila or Akkermansia spp. The phylogenetic tree is rooted using Verrucomicrobium spinosum as an outgroup and was built using PhyloPhlAn 3 [46] with 400 universal markers (see the “Methods” section). SGB, species-level genome bin (see the “Methods” section). B Within- and between-clade whole-genome average estimated nucleotide identity (fastANI [47], top panels) and full-length 16S sequence distances (bottom panels) among Akkermansia SGBs provide evidence that these are candidate species

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Genome Biology

ISSN: 1474-760X

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