Fig. 4

A HIV genome structure [60] and Icarus plots [61] for three HIV strains reconstructed by Haploflow. For each of the three reference genomes, there is one contig spanning almost the complete genome. B Radar plot of relative performance with commonly used and strain-resolved genome assembly metrics for Haploflow and 12 other methods on the HCMV benchmark data (best values are at 100%, see the “Performance evaluation” section). Haploflow, in orange, ranks first in genome fraction, strain recall, strain precision, and composite score. C Boxplots with median and interquartile range of genome fraction and NGA50 values across samples for different methods