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Fig. 3 | Genome Biology

Fig. 3

From: GRIDSS2: comprehensive characterisation of somatic structural variation using single breakend variants and structural variant phasing

Fig. 3

Consistency with copy number on large cancer cohorts. a False negative rate (FNR) inferred from the presence of SVs copy number transitions broken down by magnitude of copy number change for 1476 PCAWG samples. Comparison is between the PCAWG consensus SV/CNV call sets and GRIDSS2/PURPLE. b Inferred FNR for 3782 100x tumour samples from the Hartwig cohort. Single breakend variant calling is crucial to the low FNR in this cohort. c Comparison of expected vs actual copy number changes for the Hartwig cohort. SV inferred and actual copy number changes are closely correlated

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Genome Biology

ISSN: 1474-760X

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