Skip to main content
Fig. 1 | Genome Biology

Fig. 1

From: GRIDSS2: comprehensive characterisation of somatic structural variation using single breakend variants and structural variant phasing

Fig. 1

GRIDSS2 overview. a contigs are assembled from a single locus of reads mutually supporting the same putative break junction. If the other side cannot be uniquely determined, the contig supports a single breakend call at the break junction position. If different portions of the contig sequence uniquely align to different genomic loci, the assembly supports multiple cis phased breakpoints. b Nearby structural variants will have discordant read pairs spanning across multiple breakpoints. These generate spurious transitive calls that are collapsed into the underlying breakpoints, phasing them cis

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us