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Fig. 4 | Genome Biology

Fig. 4

From: Integration of metabolomics, genomics, and immune phenotypes reveals the causal roles of metabolites in disease

Fig. 4

Non-synonymous metabolite QTLs associated with metabolite features in healthy volunteers. a Locus zoom plot showing a non-synonymous mQTL rs35724886 located on chromosome 14. b Box plot of the top metabolite feature (m/z 331.264) associated with genotype at rs35724886. c Structural visualization of ACOT4. Sticks indicate amino acid residues involved. Amino acid change induced by mQTL (red) is predicted to clash with the neighbor amino acid (orange) with Van der Waals overlap indicated by red disks. d Locus zoom plot showing a non-synonymous mQTL rs601338 located on chromosome 19. e Box plot of the top metabolite feature (m/z 363.089) associated with genotype at rs601338

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Genome Biology

ISSN: 1474-760X

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