Fig. 1

Analysis of baseline immune parameters and molecular profiling showing baseline parameters are inter-correlated. a, b Heatmap of hierarchical clustering on correlation pattern between metabolites and immune cell counts (a GM, b BM). Cell colors indicate correlation coefficients from negative (blue) to positive (red). c Violin and boxplots showing the absolute correlation coefficient between GM and cell counts. Colors indicate cell subpopulations. d, e Heatmap of hierarchical clustering on correlation pattern between metabolites and immune modulators (d GM, e BM). Cell colors indicate correlation coefficients from negative (blue) to positive (red)