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Fig. 8 | Genome Biology

Fig. 8

From: N6-methyladenosine RNA modification regulates strawberry fruit ripening in an ABA-dependent manner

Fig. 8

Changes in m6A mRNA methylome in MTA-silenced strawberry fruits. a Venn diagrams depicting the overlap of m6A peaks from three independent m6A-seq experiments of fruits of the MTA RNAi (RNAi-MTA) and the control. b Volcano plot showing hypermethylated (red) and hypomethylated (blue) m6A peaks in the MTA-silenced fruits compared to those in the control group. c Heat map of m6A enrichment ratios of differential m6A peaks shown in b. d The distribution characteristics of differential m6A peaks shown in b. UTR, untranslated region; CDS, coding sequence. e, f Box plot of gene expression ratios (e) and cumulative distribution of gene expression changes (f) between the MTA-silenced fruits and the controls. Expression of transcripts containing hypomethylated and non-differential m6A peaks in the MTA-silenced fruits compared to the controls was analyzed based on our RNA-seq data. Asterisks indicate significant differences (***P < 0.001; Wilcoxon test). g Gene ontology (GO) enrichment for the transcripts containing hypomethylated m6A peaks in the MTA-silenced fruits compared to the control. The GO enrichment was analyzed on the agriGO database (http://systemsbiology.cau.edu.cn/agriGOv2/), and the most impacted GO biological process terms with a statistical significance of Yekutieli-corrected P value < 0.05 were shown

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