Fig. 2
From: geneshot: gene-level metagenomics identifies genome islands associated with immunotherapy response
Genomic coordinates of ICI response-associated CAGs for Odoribacter splanchnicus DSM 220712. The relative abundance of each CAG (a, b, c, i) is shown across specimens, grouping specimens by cohort (x-position) and ICI response outcome (color). The genomic coordinates of individual CAGs (d, e, f) are shown with orange arrows for the region of alignment for each gene and blue arrows with text indicating the NCBI annotations in that region. The occurrence of CAGs across multiple reference genomes (g) as well as stool microbiome specimens from this dataset (h) differentiates the core genomic elements (underlined in blue) from the accessory (or strain-specific) genetic elements (underlined in orange)