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Fig. 1 | Genome Biology

Fig. 1

From: Single cell eQTL analysis identifies cell type-specific genetic control of gene expression in fibroblasts and reprogrammed induced pluripotent stem cells

Fig. 1

Fibroblast and iPSC cluster characterisation. a This study used skin biopsies to generate fibroblasts from 79 healthy volunteers and reprogrammed them into induced pluripotent stem cell (iPSC) lines for 31 of the original 79 individuals. b Six fibroblast subtypes were identified from the transcriptional profiles of 64,018 single fibroblast cells. c The 50 TFs with the highest relative activities as identified by SCENIC in the six fibroblast subtypes. d Four iPSC subtypes were identified from 19,967 single iPSCs. e The 50 TFs with the highest relative activities as identified by SCENIC in the four iPSC subtypes. Asterisk indicates the genes used to name each subtype

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Genome Biology

ISSN: 1474-760X

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