Table 1 SCoPE2 improves quantitative accuracy, depth of proteome coverage, ease of sample preparation, and cost-effectiveness 2–10-fold over SCoPE-MS. Quantitative accuracy is evaluated by comparing relative protein ratios from in silico averaged single cells to bulk data, shown in Fig. 4c. The number of single-cell measurements per hour was estimated considering both filtering levels described in the “Methods” section. The cost of SCoPE-MS does not include the cost of sonication instrumentation. The throughput estimates for SCoPE2 are based on TMT 16-plex

From: Single-cell proteomic and transcriptomic analysis of macrophage heterogeneity using SCoPE2