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Table 1 A comparison of scMAGeCK with two available methods, MUSIC and MIMOSCA on different features

From: scMAGeCK links genotypes with multiple phenotypes in single-cell CRISPR screens

 scMAGeCK-RRAscMAGeCK-LRMUSICMIMOSCA
Analysis methodRank basedLinear modelTopic modelLinear model
PermutationYYNY
Test for certain expression-based phenotypeYYNY
Suitable for high MOINYNY
Non-linear regulatory relationshipsYNNAN
Use sgRNA-target informationYYYN
Use negative controlYYYN
R/Seurat supportYYNN