Fig. 2
From: SPIN reveals genome-wide landscape of nuclear compartmentalization
SPIN states correlate with various genomic and epigenomic features. a Stratification of histone marks and Hi-C subcompartments as compared to SPIN states. Heatmap shows signal fold enrichment calculated as the ratio of observed signals over expected. K562 subcompartment annotations are produced by SNIPER [15]. b Most frequently observed SPIN state boundary transition patterns. We count the percentage of different SPIN boundary patterns where symmetrical patterns are merged. c Histone marks (H3K27ac, H3K4me1, H3K27me3, and H3K9me3) on SPIN state transition boundaries. d Violin plot of transcript levels based on GRO-seq in different SPIN states. e Transcript levels based on GRO-seq over three consecutive SPIN states. Three consecutive SPIN states are normalized by length (mean: blue line; standard deviation: gray)