Fig. 3

Bichrom decomposes sequence and preexisting chromatin predictors at individual Ascl1 binding sites. a Bichrom network-derived latent representation of induced Ascl1 binding events (orange) and a randomly sampled subset of unbound genomic regions (gray). The axes represent contributions of the Bichrom_SEQ sub-network and the Bichrom_CHR sub-network toward bimodal network predictions. b Distributions of Bichrom_CHR scores for Ascl1 binding events conditioned on the Bichrom_SEQ scores