Fig. 3
From: GCNG: graph convolutional networks for inferring gene interaction from spatial transcriptomics data
Spatial expression patterns for selected ligand-receptor pairs. a, b Spatial expression distribution of correctly predicted positive (cd93) and negative (hrh3) receptors for ligand col4a1. Two of the 7 fields of view (FOV) profiled are shown (see Additional file 1: Fig. S4 for all FOVs). As can be seen, the correctly predicted pairs are indeed much better spatially correlated than the negative pair. c, d Spatial expression distribution of correctly predicted positive (itgb1) and negative (lyve1) receptors for ligand lamc1. Cells highly expressing lamc1 and itgb1 are both concentrated in the 5th and 7th fields as shown