Fig. 3

Phylogenomic analysis of human oral TM7 with all TM7 genomes on the NCBI’s GenBank shows association of plaque TM7 with environmental genomes, and tongue TM7 with TM7 from animal stool. The phylogenetic tree at the top of the figure was computed using ribosomal proteins and includes 5 Firmicutes as an outgroup. Regions of the tree that are associated with either plaque or tongue clades from Fig. 2 are marked with green or blue shaded backgrounds respectively. Bootstrap support values are shown next to branches separating major oral clades. Subclades are marked with rectangles below the branches they represent. The layers below the tree provide additional information for each genome. From top to bottom: Clade: the clade associations for finer groupings of oral genomes. Oral Site: the oral site with which the genome is associated is shown for our MAGs in accordance with Fig. 2. Source: the source of the genome, where red is human oral; brown, animal gut; cyan, dolphin oral; and black, environmental samples. Reference: the genomes from this study in blue, and genomes from Parks et al. in gray [50]. The majority of the rest of the genomes originate from various publications from the Banfield Lab at UC Berkeley. The insert at the top right of the figure shows boxplots for ANI results for genomes in each subclade against all other genomes. Data points represent the ANI score for comparisons in which the alignment coverage was at least 25%. Within-subclade comparisons appear in green, and between-subclades comparisons appear in red