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Fig. 5 | Genome Biology

Fig. 5

From: Multiomics profiling of primary lung cancers and distant metastases reveals immunosuppression as a common characteristic of tumor cells with metastatic plasticity

Fig. 5

Immune cell infiltration in primary lung cancers versus metastases by deconvolution of transcriptomic profiles. a The overall immune cell infiltration was inferred by RNA-seq data using ESTIMATE. bg The immune cell subsets were inferred by deconvolution of RNA-seq data using TIMER. The y axis represents the proportion of each immune cell type in the specimen. h The CD4/CD8 ratio inferred using TIMER. The difference was assessed by the paired-sample Wilcoxon test

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