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Fig. 7 | Genome Biology

Fig. 7

From: Mustache: multi-scale detection of chromatin loops from Hi-C and Micro-C maps using scale-space representation

Fig. 7

a The consistency between MUSTACHE loops detected using Micro-C and Hi-C data in HFFc6 cell line using a fixed q value threshold of 0.01, shown as a Venn diagram. b The consistency plot for MUSTACHE results between Hi-C and Micro-C for the top-k reported interactions for each contact map. The APA plots for MUSTACHE loops in HFFc6 cell line for c Hi-C and d Micro-C data. The APA score for the enrichment of center is reported above each plot. MUSTACHE reported loops in Hi-C (lower triangular) and Micro-C (upper triangular) of HFFc6 for e the top 16,132 significant interactions, and f a fixed q value threshold of 0.01. The loop call marked by a “ ” was in common between Hi-C and Micro-C, but was detected at a smaller scale and has a stronger enrichment in Micro-C compared to Hi-C. The loops that are uniquely detected in either by Hi-C or by Micro-C are denoted by black arrows

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