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Table 2 The repertoire of immune genes of Aedes albopictus. Comparison in the number of immune-related genes among Ae. albopictus (Alb, AalbF2, and AaloF1 assemblies), Ae. aegypti (Aae, AaegL5), Anopheles gambiae (Ag, AgamP4), and Dr. melanogaster (Dm, Dmel_r6.29). The numbers in parentheses are the total number of genes after manually excluding suspected artifacts

From: Improved reference genome of the arboviral vector Aedes albopictus

Gene family or pathway AalbF2 AaloF1 Aae Ag Dm
Antimicrobial peptides (AMPs) 6 11 16 11 7
Autophagy pathway members (APHAGs) 30 (28) 21 20 21 20
Caspase activators (CASPAs) 3 4 4 2 5
Caspases (CASPs) 24 (18) 12 10 15 7
Catalases (CATs) 2 2 2 1 2
CLIP-domain serine proteases (CLIP) 118 (109) 107 82 64 48
C-type lectins (CTLs) 66 (63) 48 44 27 35
Fibrinogen-related proteins (FREPs) 52 (50) 49 38 53 17
Galectins (GALEs) 12 15 12 8 5
Gram-negative binding proteins (GNBPs) 13 13 7 7 3
Heme peroxidases (HPXs) 36 (34) 20 23 23 21
IMD pathway members 16 (13) 11 10 7 8
Inhibitors of apoptosis (IAPs) 5 5 5 7 4
JAK/STAT pathway members (JAKSTATs) 3 4 3 3 3
Lysozymes (LYSs) 7 (6) 9 7 8 11
MD2-like proteins (MLs) 36 26 27 18 10
Peptidoglycan recognition P. (PGRPs) 18 (16) 13 10 7 13
Prophenoloxidase (PPOs) 23 (20) 16 14 9 3
Rel-like NFkappa-B proteins (RELs) 4 4 3 2 3
Scavenger receptor (SCRs) 28 (27) 20 18 16 22
Serine protease inhibitors (SRPNs) 46 (45) 30 26 17 29
Small Reg. RNA pathway Mem. (SRRPs) 51 (49) 41 39 26 24
Superoxide dismutase (SOD) 9 9 6 4 4
Spaetzle (SPZ) 13 13 9 6 6
Thioester (TE)-containing proteins (TEP) 7(5) 3 6 10 6
Toll pathway members (TOLLPATHs) 10 7 6 5 5
Toll receptors (TOLLs) 26 (23) 14 12 9 9
Total 663 (622) 527 459 386 344