Table 2 The repertoire of immune genes of Aedes albopictus. Comparison in the number of immune-related genes among Ae. albopictus (Alb, AalbF2, and AaloF1 assemblies), Ae. aegypti (Aae, AaegL5), Anopheles gambiae (Ag, AgamP4), and Dr. melanogaster (Dm, Dmel_r6.29). The numbers in parentheses are the total number of genes after manually excluding suspected artifacts
From: Improved reference genome of the arboviral vector Aedes albopictus
Gene family or pathway | AalbF2 | AaloF1 | Aae | Ag | Dm |
|---|---|---|---|---|---|
Antimicrobial peptides (AMPs) | 6 | 11 | 16 | 11 | 7 |
Autophagy pathway members (APHAGs) | 30 (28) | 21 | 20 | 21 | 20 |
Caspase activators (CASPAs) | 3 | 4 | 4 | 2 | 5 |
Caspases (CASPs) | 24 (18) | 12 | 10 | 15 | 7 |
Catalases (CATs) | 2 | 2 | 2 | 1 | 2 |
CLIP-domain serine proteases (CLIP) | 118 (109) | 107 | 82 | 64 | 48 |
C-type lectins (CTLs) | 66 (63) | 48 | 44 | 27 | 35 |
Fibrinogen-related proteins (FREPs) | 52 (50) | 49 | 38 | 53 | 17 |
Galectins (GALEs) | 12 | 15 | 12 | 8 | 5 |
Gram-negative binding proteins (GNBPs) | 13 | 13 | 7 | 7 | 3 |
Heme peroxidases (HPXs) | 36 (34) | 20 | 23 | 23 | 21 |
IMD pathway members | 16 (13) | 11 | 10 | 7 | 8 |
Inhibitors of apoptosis (IAPs) | 5 | 5 | 5 | 7 | 4 |
JAK/STAT pathway members (JAKSTATs) | 3 | 4 | 3 | 3 | 3 |
Lysozymes (LYSs) | 7 (6) | 9 | 7 | 8 | 11 |
MD2-like proteins (MLs) | 36 | 26 | 27 | 18 | 10 |
Peptidoglycan recognition P. (PGRPs) | 18 (16) | 13 | 10 | 7 | 13 |
Prophenoloxidase (PPOs) | 23 (20) | 16 | 14 | 9 | 3 |
Rel-like NFkappa-B proteins (RELs) | 4 | 4 | 3 | 2 | 3 |
Scavenger receptor (SCRs) | 28 (27) | 20 | 18 | 16 | 22 |
Serine protease inhibitors (SRPNs) | 46 (45) | 30 | 26 | 17 | 29 |
Small Reg. RNA pathway Mem. (SRRPs) | 51 (49) | 41 | 39 | 26 | 24 |
Superoxide dismutase (SOD) | 9 | 9 | 6 | 4 | 4 |
Spaetzle (SPZ) | 13 | 13 | 9 | 6 | 6 |
Thioester (TE)-containing proteins (TEP) | 7(5) | 3 | 6 | 10 | 6 |
Toll pathway members (TOLLPATHs) | 10 | 7 | 6 | 5 | 5 |
Toll receptors (TOLLs) | 26 (23) | 14 | 12 | 9 | 9 |
Total | 663 (622) | 527 | 459 | 386 | 344 |