Skip to main content
Fig. 3 | Genome Biology

Fig. 3

From: Genome-wide identification of genes regulating DNA methylation using genetic anchors for causal inference

Fig. 3

a Enrichment (odds ratio) for transcription factors among identified genes with either 1, 2, 3–5, or more than 5 target CpGs. Error bars represent 95% confidence intervals. b Transcription factor binding site enrichment; each dot represents a transcription factor, with on the x-axis the logarithm of the number of target CpGs for that transcription factor (at a gene-level significance level; P < 1.2 × 10−7), and on the y-axis the odds ratio for the enrichment of the target CpGs in its experimentally determined binding sites (ChIP-seq). The size of the dots represents the significance (FDR), and TFs for which the target CpGs were significantly enriched in its binding sites are colored in blue

Back to article page

Genome Biology

ISSN: 1474-760X

Contact us