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Table 2 scRATE classification of genes in the heart data

From: Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics

Threshold

Selected model

 

P

NB

ZIP

ZINB

(a)

0 SE

1111

2930

525

949

1 SE

2112

3183

81

139

2 SE

2930

2509

5

71

3 SE

3445

2035

1

34

(b)

0 SE

1523

2317

518

1105

1 SE

2733

2583

63

84

2 SE

3544

1913

3

3

3 SE

4000

1461

0

2

(c)

0 SE

1118

2745

478

1094

1 SE

2107

3108

88

132

2 SE

2930

2432

5

68

3 SE

3420

1981

1

33

  1. Genes were classified as one of four count models (P, NB, ZIP, or ZINB) using four levels of stringency (0 SE, 1 SE, 2 SE, or 3 SE). Table shows the number of genes in each category using a GLM with only the offset term to account for cell sequencing depth (a), using a GLM that also includes cell type as an explanatory covariate (b), and using a GLM that includes offset as well as a randomly shuffled cell type as a covariate (c). See Additional file 1: Tables S3 and S4 for the results with the mouse kidney and the human PBMC datasets