Fig. 4
From: Bayesian model selection reveals biological origins of zero inflation in single-cell transcriptomics
Effect of accounting for cell type on estimated zero inflation and overdispersion. a The scatterplot shows estimated zero inflation \(\widehat {\pi }_{0}\) before and after including cell type in the GLM with ZINB error model. Color coding indicates the ZI classification of genes (1 SE) before and after accounting for cell type. The red point (ZI:ZI) at 0.3 on the diagonal is Xist. The light blue point (NotZI:NotZI) to the right is Ddx3y. b The scatterplot shows the estimated overdispersion \(\hat {r}\) before and after including cell type in the GLM with NB error model