Fig. 5

Identification of methylation patterns associated with CMT2 and DRM2 in multiple species. a Distribution of TEs in multiple species according to pattern score. Single peaks indicate the identification of only one pattern signal; two peaks indicate the presence of two pattern signals. b TE methylation variation features in P. patens and M. polymorpha that lack a peak aligned with DRM2-associated patterns, alongside CHH methylation mutants from A. thaliana (denoted “At”). c, d Differences of region among-site sd. and read methylation sd. among M. polymorpha, P. patens and CHH methylation mutants of A. thaliana (denoted "At"), with respect to region methylation: lines represent the average among-site sd. c or read methylation sd. d of a region for a given methylation level. All regions are plotted (i.e. without a minimal methylation level). e Analysis of the pattern score of exon CH methylation in human samples from the frontal cortex [39]. f Methylation variation features of individual exons in human samples from e