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Fig. 6 | Genome Biology

Fig. 6

From: Quantile normalization of single-cell RNA-seq read counts without unique molecular identifiers

Fig. 6

Quasi-UMI counts approximate UMI counts more closely than census counts. QUMI normalization with Poisson-lognormal target distribution was applied to read counts from three datasets. qumi_custom: shape parameter (1.9 for Macosko, 2.4 for Tung and Zheng) set by maximum likelihood fit to matched training data from same tissue type. qumi_default: shape parameter set to 2.0 for all datasets

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