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Fig. 2 | Genome Biology

Fig. 2

From: Analysis of endothelial-to-haematopoietic transition at the single cell level identifies cell cycle regulation as a driver of differentiation

Fig. 2

scRNA-seq reveals distinct cell types generated during hPSC differentiation. a Heatmap of the marker genes for each cluster. For this analysis, data from EHT D3 and EHT D5 were merged. b tSNE plots showing comparison of samples collected at EHT D3 and EHT D5. Four populations were identified based on transcriptional identity. Pie charts are showing the percentage and absolute number (in brackets) of cells in each cluster. Transcriptional data was used to order cells along differentiation trajectories, from endothelial cells (right) to the haematopoietic and mesenchymal branches (left). c tSNE plots of merged data from EHT D3 and EHT D5. Expression of relevant lineage markers is shown

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Genome Biology

ISSN: 1474-760X

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