Whole-genome sequencing of glioblastoma reveals enrichment of non-coding constraint mutations in known and novel genes

Table 1 Summary of SweGBM-1 (n = 39) cohort with somatic point and indel mutations statistics

HGCC-ID	Glioma Grade*	Age	Sex	Survival days (diagnosis to death)	Subtype classification of the cell line	Tumor purity (aberrant cell fraction)	Depth of coverage	MuTect2-Strelka concordant SPM	MuTect2-Strelka concordant SIM
3004	IV	70	M	134	CL	89	72	7788	330
3009	IV	60	M	174	CL	72	75	9037	359
3013	IV	78	F	122	PN	83	78	8477	308
3039	IV	38	M	994	CL	98	77	7167	266
3046	IV	73	M	186	CL	71	74	8587	336
3048	IV	77	M	279	CL	99	72	9266	431
3053	IV	64	M	277	MS	64	72	4201	157
3065	IV	77	M	127	MS	84	86	14,666	450
3071	IV	65	M	309	MS	82	70	9461	386
3078	IV	51	M	716	MS	68	79	3729	170
3082	IV	70	F	314	PN	95	89	10,122	385
3086	IV	72	M	444	CL	86	72	5850	373
3100	IV	73	M	284	CL	95	68	5028	74
3102	IV	64	F	543	MS	96	75	7456	285
3104	IV	59	M	585	CL	54	73	9661	347
3123	IV	64	M	1613	CL	94	79	12,224	364
3137	IV	74	M	1088	MS	46	78	5819	227
3151^†	IV	61	M	817	MS	73	67	230,968	1562
3164	IV	68	M	54	PN	91	81	8661	439
3172	IV	50	M	1352	CL	78	78	4312	164
3173	IV	73	F	229	MS	51	64	5345	211
3177	IV	74	F	179	n/a	99	78	10,585	522
3179^†	IV	63	M	474	CL	64	69	4696	325
3187	IV	70	M	193	PN	62	73	4481	194
3189	IV	83	M	218	CL	98	75	7710	444
3198	IV	60	M	729	PN	75	78	7968	308
3202	IV	66	M	137	MS	84	67	5361	324
3206	IV	61	M	767	PN	71	83	4025	246
3211	IV	72	F	206	CL	61	75	5151	265
3220	IV	73	F	492	MS	70	79	4447	268
3233^†	IV	53	M	809	MS	100	68	1590	189
3235	IV	56	M	141	MS	94	71	4570	203
3242	IV	50	M	449	MS	91	85	4336	246
3243^†	IV	43	M	1070	PN	41	81	828	296
3253	IV	69	M	92	CL	79	78	8079	358
3266	IV	54	M	571	n/a	85	76	4767	259
3274	IV	74	M	206	MS	68	69	6447	227
3279	IV	56	M	333	MS	41	78	6320	64
3291	IV	60	F	1527	CL	89	79	7782	327

ISSN: 1474-760X