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Fig. 4 | Genome Biology

Fig. 4

From: Approaches for integrating heterogeneous RNA-seq data reveal cross-talk between microbes and genes in asthmatic patients

Fig. 4

Method of LDA-link for predicting links between genes and microbes. a The method for identifying a pseudo-gold standard training dataset through identifying a set of very strong linear correlations and an equal number of very low correlations. b Gene set enrichment of the pseudo-gold standard genes shows enrichment in pathways related to asthma. The x-axis is the -log(p value). c The importance of features (LDA topics for genes and microbes) in the randomForest model by Gini index. The top 20 associated gene in topic 8 (d) and topic 7 (e) of genes, and topic 1 (f) of microbes

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Genome Biology

ISSN: 1474-760X

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