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Fig. 5 | Genome Biology

Fig. 5

From: PTWAS: investigating tissue-relevant causal molecular mechanisms of complex traits using probabilistic TWAS analysis

Fig. 5

Discovery in PTWAS scan by traits. The results are from the analysis of GTEx eQTL data in 49 tissues and 114 complex traits using the PTWAS scan. Each point represents the number of rejected genes at the 5% FDR level for the corresponding trait. The distribution is highly skewed: a large proportion of tested genes are rejected in polygenic traits like heights, whereas few rejections are reported for >20 traits

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Genome Biology

ISSN: 1474-760X

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