Fig. 3

Recall and precision for calling somatic deletions on simulated data. Results are grouped by deletion length, denoted as interval at the top of the plot. For our approach (Varlociraptor+*), curves are plotted by scanning over the posterior probability for having a somatic tumor variant (for readability, each curve is terminated by a square mark). For other callers that provide a score to scan over (e.g., p value for Lancet), we plot a dotted line. Ad hoc results are shown as single dots. Results are shown if the prediction of the caller did provide at least 10 calls. The sharp curves for our approach reflect the favorable property of having a strong separation between the probabilities of true and false positives, see Fig. 4