Fig. 5

Diagrams of 3-, 4-, and 5-body chromatin interactions. a–c Diagrams illustrating 3-, 4-, and 5-body chromatin interactions respectively (green and blue dots). Gray arrows represent spatial Euclidean distances within 80 nm [47]. The principal loop is the longest loop (in bp) among chromatin regions forming a many-body (≥3) interaction, and genomic regions serving as anchors of principal loops are represented by green dots