Fig. 7
Restriction of the teg block by spacers and correlation with CRISPR-Cas systems. a Top panel: median survival of adult C. elegans worms exposed to the studied collection of P. aeruginosa strains (with 95% confidence interval, C.I.). The strains are ordered from high to low virulence (left to right) and aligned with the matrix below. Bottom left panel: gene presence/absence matrix for genes targeted by CRISPR spacers. Gene presence is indicated with black squares and absence with white squares. Genes (rows) are aligned with the corresponding p values. Bottom right panel: Association statistics (p value of MW and LR tests) for the CRISPR-targeted genes, shown as |log10(pval)|. Rows are ordered from association with high virulence to association with low virulence. b Schematic of the teg block in strain z8. Black boxes indicate teg genes and arrowheads spacers that target the element. c Number of strains (i.e., count) where the teg block is present or absent in relationship with the status of the host CRISPR-Cas system (active in red color, inactive in cyan color). The p value of a chi-square test is indicated