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Fig. 1 | Genome Biology

Fig. 1

From: Impact of mouse contamination in genomic profiling of patient-derived models and best practice for robust analysis

Fig. 1

Impact assessment of mouse genome on human genome analysis. a Schematic overview of the data production to simulate mouse contaminated sample. b Coverage of five mouse samples on human genome reference (hg19). c Top ranked human functional gene sets enriched by mouse reads. Functional terms are annotated by Gene Ontology (GO). d Distributions of mouse read RPKM in all genes targeted by WES kit, Cancer Gene Census genes, and genes containing cancer hotspot mutations defined in cancer hotspots

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Genome Biology

ISSN: 1474-760X

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