Fig. 3

Identification of experimentally validated fusions in breast cancer cell lines BT474, KPL4, MCF7, and SKBR3. a All fusions identified by at least three different methods are shown and ranked from being predicted by fewest to most methods in an UpSetR [61] style plot (UpSetR code forked and modified to show individual fusion group memberships here [62]). Previously reported experimentally validated fusions are shaded to facilitate identification. b Bar plot showing the number of experimentally validated fusions (left axis) contained within the union of all predictions supported by at least the specified number of fusion prediction methods. Also shown is the corresponding percent of the union of predictions containing experimentally validated fusions (blue line, right axis)