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Table 1 Overview of specifications for inferred regulatory networks. In order: the adaptive correlation threshold set to retain significant correlations; average detected genes, number of edges, and percentage of negative edges; number of nodes and percentage of nodes being “regulators of transcription”; network density (ratio edges/nodes), number of connected components, average shortest path, and modularity

From: Single-cell transcriptomics unveils gene regulatory network plasticity

Network Corr. Tresh. Avg. det. genes Edges Edges < 0 (%) Nodes RT % E/N Conn. Comp. Avg. short. path Modularity
Marrow 0.95 3152 48,748 0.0 3221 27.5 15.13 3 4.06 0.37
Intestine 0.94 4046 60,941 0.0 5858 24.4 10.40 1 6.33 0.49
Heart 0.94 2682 3460 0.4 1519 23.7 2.28 3 6.71 0.75
Brain 0.92 3195 23,492 0.0 5131 27.3 4.58 2 9.84 0.73
Fat 0.89 3409 35,495 1.4 4814 26.7 7.37 3 5.27 0.42
Mammary 0.95 3623 38,088 1.2 5978 26.0 6.37 2 7.92 0.64
Skin 0.85 3410 42,965 8.6 5361 28.6 8.01 1 5.56 0.59
Spleen 0.88 1839 30,424 3.4 4560 28.8 6.67 1 6.95 0.43
Pancreas 0.92 4408 30,191 0.5 6586 24.6 4.58 1 8.84 0.75
Bladder 0.99 4873 46,136 26.2 5729 22.8 8.05 5 7.19 0.52
Lung 0.90 2546 15,008 0.6 2921 25.7 5.14 2 7.73 0.66
Pancreas, healthy 0.90 5580 48,540 1.1 7432 28.0 6.53 2 7.06 0.58
Pancreas, T2D 0.91 6636 52,035 6.7 7501 27.0 6.94 1 6.63 0.57
Microglia, healthy 0.89 625 32,064 0.0 2665 31.6 12.03 3 4.16 0.45
Microglia, AD 0.84 676 20,970 0.0 2774 26.7 7.56 1 6.74 0.65