Fig. 1From: Melissa: Bayesian clustering and imputation of single-cell methylomesMelissa model overview. Melissa combines a likelihood computed from single-cell methylation profiles fitted to each genomic region using a supervised regression approach (bottom left) and an unsupervised Bayesian clustering prior (top left). The posterior distribution provides a methylome-based clustering (top right) and imputation (bottom right) of single cellsBack to article page