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Fig. 1 | Genome Biology

Fig. 1

From: EmptyDrops: distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data

Fig. 1

Cell-calling results from different algorithms in simulations based on the PBMC dataset. Simulation scenarios are labelled as G1/G2 where G1 and G2 are the number of barcodes in the group of large and small cells, respectively. a The recall for each method, defined as the proportion of detected cells from each group. EmptyDrops was used with an FDR threshold of 0.1%. b The observed FDR in the set of libraries detected by EmptyDrops at a range of nominal FDR thresholds (dotted lines), defined as the proportion of detected droplets that are empty. In both plots, each point represents the result of one simulation iteration, the bar represents the mean value across 10 iterations, and the error bars represent the standard error of the mean

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