Fig. 2
From: dStruct: identifying differentially reactive regions from RNA structurome profiling data
dStruct identifies differentially reactive regions. a Users input samples of reactivity profiles, some from group A and some from group B. b In the first step, dStruct quantifies the within-group and between-group variations in terms of d scores. c In the second step, dStruct identifies regions where the between-group variation appears to be greater than the within-group variation. These are highlighted by purple background. This step is skipped if users provide a list of candidate regions. d Reactivity profiles for one of the candidate regions. e In the third step, dStruct compares the dwithin and dbetween profiles using a Wilcoxon signed-rank test. f The results are output as a list of region identifiers, such as the start and end locations of the candidates tested, and the p values and q values for each region