Fig. 3

Comparison of target prediction algorithms using microarray data. Microarray profiling data were analyzed to identify target upregulation resulting from concurrent inhibition of 25 miRNAs. a Correlation of target upregulation and target prediction scores computed by 5 individual algorithms, as measured by Pearson correlation coefficient. b Average level of expression upregulation for predicted targets. For each algorithm, 100 top-scoring predicted targets per miRNA on average were included in the analysis